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Editorial

Open Access

Obesity is an independent risk factor for low serum testosterone in adult males

  • Mohamad Habous1
  • Alaa Tealab2
  • Mohamed Ali3
  • Amir Abdel Raheem4
  • David Ralph4
  • Saleh Binsaleh5

1urologist with Elaj Medical Group, Jedda Saudi Arabia

2urologist with the Urology Department, Zagazig University, Egypt

3urologist in the Urology Department at Tudor Bilharz Institute, Giza, Egypt

4urologists at the St. Peter’s Andrology Centre, London, United Kingdom

5urologist in the Division of Urology, Department of Surgery, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia

DOI: 10.31083/jomh.v11i5.15 Vol.11,Issue 5,October 2015 pp.30-34

Published: 05 October 2015

*Corresponding Author(s): Saleh Binsaleh E-mail: binsaleh@ksu.edu.sa

PDF (111.28 kB)

Abstract

Objectives: Obesity and increased weight are recognized risk factors of hypogonadism. This study looked into the relation between body mass index (BMI) and serum testosterone level.

Patients and Methods: This was a prospective study of 664 patients. All patients had BMI calculation and serum Testosterone measurement. Patients with any other possible cause for hypogonadism were excluded from the study.

Results: Statistical analysis of the results showed an inverse correlation between the BMI and serum testosterone.

Conclusion: Increasing BMI is an independent risk factor in lowering serum testosterone.

Keywords

Hypogonadism, Metabolic Syndrome, Lifestyle medicine

Cite and Share

Mohamad Habous,Alaa Tealab,Mohamed Ali,Amir Abdel Raheem,David Ralph,Saleh Binsaleh. Obesity is an independent risk factor for low serum testosterone in adult males. Journal of Men's Health. 2015. 11(5);30-34.

References

1. World Health Organization, WHO, Global Strategy on Diet, Physical Activity and Health,2003 http://www.who.int/dietphysicalactivity/publications/facts/obesity/en

2. WHO. Obesity: Preventing and managing the global epidemic. WHO Technical Report Series Number 894. WHO: Geneva, 2000.

3. Flegal KM, Carroll MD, Ogden CL, Johnson CL. Prevalence and trend in obesity among US adults, 1999–2000. JAMA 2002; 288: 1723–1727.

4. James WTP, Rigby N, Leach R. The obesity epidemic, metabolic Syndrome and future prevention strategies. Eur J Cardiovasc Prev Rehabil 2004; 11: 3–8.

5. Peeters A, Bartender JJ, Willekens F, Mackenbach JP, Al Mamun A, Nonneux 

L. NEDCOM, the Netherlands epidemiology and demographic compression on morbidity research group. Obesity in adulthood and its consequences for life expectancy: a life-table analysis. Ann Intern Med 2003; 138: 24–32. 

6. World Health Organization, WHO, Fact sheet N°311 September 2006 Obesity and overweight http://www.who.int/mediacentre/factsheets/fs311/en/index. html

7. Kaufman JM, Vermeulen A. The decline of androgen levels in elderly men and its clinical and therapeutic implications. Endocr Rev 2005; 26: 833-876.

8. Gapstur SM, Gann PH, Kopp P, Colangelo L, Longcope C, Liu K. Serum androgen concentrations in young men: a longitudinal analysis of associations with age, obesity, and race. The CARDIA male hormone study. Cancer Epidemiol Biomarkers Prev 2002; 11(10 Part 1): 1041–1047.

9. Andre B. Araujo, Gretchen R. Esche, Varant Kupelian, Amy B. O’Donnell, Thomas G. Travison, Rachel E. Williams, Richard V. Clark and John B. Prevalence of Symptomatic Androgen Deficiency in Men. The Journal of Clinical Endocrinology & Metabolism Vol. 92, No. 11 4241-4247.

10. Snyder PJ. Causes of primary of hypogonadism in males. http://www.uptodate. com/patients/content/topic.do?topicKey=~eL_hWzgiC9MgqX

11. Snyder PJ. Causes of secondary hypogonadism in males. http://www.uptodate. com/patients/content/topic.do?topicKey=~6ZnI AcJrzRkJXZ

12. Kapoor D, Aldred H, Clark S, Channer KS, Jones TH. Clinical and biochemical assessment of hypogonadism in men with type 2 diabetes: correlations with bioavailable testosterone and visceral adiposity. Diabetes Care. 2007 Apr;30(4):911-7

13. Kloner RA. Erectile dysfunction as a predictor of cardiovascular

disease. Int J Impot Res 2008; 20: 460-465.

14. Thompson IM, Tangen CM, Goodman PJ, Probstfield JL, Moinpour CM, Coltman CA. Erectile dysfunction and subsequent cardiovascular disease. JAMA 2005; 294: 2996-3002.

15. Svartberg J, Midtby M, Bonaa KH, Sundsfjord J, Joakimsen RM, Jorde R. The associations of age, lifestyle factors and chronic disease with testosterone in men: the Tromso study. Eur J Endocrinol 2003; 149: 145-152.

16. Allan CA, Strauss BJ, McLachlan RI. Body composition, metabolic syndrome and testosterone in ageing men. Int J Impot Res 2007; 19: 448–457.

17. Allen NE, Appleby PN, Davey GK, Key TJ. Lifestyle and nutritional determinants of bioavailable androgens and related hormones in British men. Cancer Causes Control 2002; 13: 353–363.

18. Gapstur SM, Gann PH, Kopp P, Colangelo L, Longcope C, Liu K. Serum androgen concentrations in young men: a longitudinal analysis of associations with age, obesity, and race. The CARDIA male hormone study. Cancer Epidemiol Biomarkers Prev 2002; 11(10 Part 1): 1041–1047.

19. Jensen TK, Andersson AM, Jorgensen N, Andersen AG, Carlsen E, Petersen JH et al. Body mass index in relation to semen quality and reproductive hormones among 1,558 Danish men. Fertil Steril 2004; 82: 863–870.

20. K Esposito, F Giugliano, M Ciotola, M De Sio, M D’Armiento and D Giugliano. Obesity and sexual dysfunction,male and female. International Journal of Impotence Research (2008) 20, 358–365.

21. Svartberg J. Epidemiology: testosterone and the metabolic syndrome. Int J Impot Res 2007; 19: 124–128.

22. Allan CA, Strauss BJ, McLachlan RI. Body composition, metabolic syndrome and testosterone in ageing men. Int J Impot Res 2007; 19: 448–457.

23. Feldman HA, Longcope C, Derby CA, Johannes CB, Araujo AB, Coviello AD et al. Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts Male Aging Study. J Clin Endocrinol Metab 2002; 87: 589-598.

24. Sandeep Dhindsa, Sathyavani Prabhakar, Manak Sethi, Arindam Bandyopadhyay, Ajay Chaudhuri and Paresh Dandona. Frequent Occurrence of Hypogonadotropic Hypogonadism in Type 2 Diabetes. The Journal of Clinical Endocrinology & Metabolism Vol. 89, No. 11 5462-5468.

25. B.B. Yeap, Are Declining Testosterone Levels A Major Risk Factor for Ill-Health in Aging Men? Int J Impot Res. 2009;21(1):24- 36.

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