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Case Report

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Laparoscopic isolated caudate lobectomy of two symptomatic familiar giant liver hemangiomas, case reports and literature review

  • Alessandro Anselmo1
  • Daniele Sforza2
  • Marco Pellicciaro3
  • Carlo Gazia3
  • Angelo Gabriele Epifani4
  • Leandro Siragusa3
  • Laura Tariciotti1
  • Alessandro Parente3
  • Giuseppe Tisone3

1HBP and Transplant Unit, Policlinico Tor Vergata, 00133 Rome, Italy

2Department of Emergency, Policlinico Tor Vergata Hospital, 00133 Rome, Italy

3Department of Surgical Science, University Tor Vergata, 00133 Rome, Italy

4Department of Surgery, University of Milano, 20122 Milano, Italy

DOI: 10.31083/jomh.2021.109 Vol.17,Issue 4,September 2021 pp.310-315

Submitted: 16 April 2021 Accepted: 17 May 2021

Published: 30 September 2021

*Corresponding Author(s): Alessandro Anselmo E-mail:

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Background and objective: Liver hemangioma (LH) is the most common benign tumour of the liver, but its origin is still not clear and not much is known about a possible familiarity. Caudate lobectomy is the most effective surgical treatment for benign tumors arisen in segment I. The occurrence of giant LH within the same liver segments in different members of the same family has never been described in literature. Herein we report the first two consecutive laparoscopic caudate lobectomy for familiar giant LH in a father and his daughter.

Methods: The father showed a lesion in the caudate lobe (CL) suggestive of LH steadily grown, asymptomatic for 24 years until it has caused abdominal discomfort and pain (Dmax 89 mm). The daughter showed multiple hepatic hemangiomas with the biggest one located in the CL compressing the inferior vena cava (Dmax 88 mm).

Results: Despite the size of the masses, we opted for a pure laparoscopic approach and a caudate lobectomy was performed in both cases. Operation time was 140 and 180 min. Patients had an uneventful recovery and a good outcome after the scheduled follow up exams 6 months after the procedure.

Conclusions: A chance of familiarity transmission for hemangiomas exists and therefore should be further investigated. Laparoscopic isolated caudate lobectomy for symptomatic GLH is feasible and safely performed on selected patients by experienced hepatobiliary surgeons. Prospective randomized studies on larger populations are needed to assess if this minimally invasive approach can be proposed as a standard of care for S-I LH.


Familial liver hemangioma; Laparoscopic liver surgery; Caudate lobe

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Alessandro Anselmo,Daniele Sforza,Marco Pellicciaro,Carlo Gazia,Angelo Gabriele Epifani,Leandro Siragusa,Laura Tariciotti,Alessandro Parente,Giuseppe Tisone. Laparoscopic isolated caudate lobectomy of two symptomatic familiar giant liver hemangiomas, case reports and literature review. Journal of Men's Health. 2021. 17(4);310-315.


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