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Risks and subgroups of cognitive impairment under different marital status among older adults: a latent profile analysis

  • Yang Xiong1,2,†
  • Yangchang Zhang3,†
  • Fuxun Zhang1,2
  • Changjing Wu1
  • Xiaoyingzi Huang1
  • Feng Qin1
  • Jiuhong Yuan1,2

1Andrology Laboratory, West China Hospital, Sichuan University, 610041 Chengdu, Sichuan, China

2Department of Urology, West China Hospital, Sichuan University, 610041 Chengdu, Sichuan, China

3Department of Epidemiology and Health Statistics, School of Public Health and Management, Chongqing Medical University, 400016 Chongqing, China

DOI: 10.31083/jomh.2021.092 Vol.17,Issue 4,September 2021 pp.234-242

Submitted: 25 May 2021 Accepted: 07 July 2021

Published: 30 September 2021

*Corresponding Author(s): Jiuhong Yuan E-mail:

† These authors contributed equally.

PDF (4.1 MB) Supplementary material


Background and objective: With aging, cognitive impairment is severe in the aging society. This paper aimed to investigate the association between cognitive impairment and marital status and the empirical typology of cognitive impairment in Chinese aging population.

Methods: Descriptive statistics were performed by retrieving data from the China Health and Retirement Longitudinal Study (CHARLS) to test the relation between cognitive impairment and marital status with univariate linear regression and multivariate linear regression. The subgroups of cognitive impairment for included older subjects were identified with latent profile analysis (LPA).

Results: The sample included 13,149 participants aged 40 years or older. Both unmarried males and females suffer lower cognitive function than married males and females (P < 0.001). The declining trend remained consistent (P < 0.05) after adjustment for covariates. The participants who were illiterate or older or agricultural hukou had lower cognitive functions than their counterparts. LPA results showed that the cognitive function of participants could be divided into three subgroups.

Conclusions: Unmarried males and females had lower cognitive function than that of married counterparts due to the declined percentage of class two, who have high mental intactness and episodic memory.


Cognitive impairment; Latent profile analysis; Marital status; Older adults

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Yang Xiong,Yangchang Zhang,Fuxun Zhang,Changjing Wu,Xiaoyingzi Huang,Feng Qin,Jiuhong Yuan. Risks and subgroups of cognitive impairment under different marital status among older adults: a latent profile analysis. Journal of Men's Health. 2021. 17(4);234-242.


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