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Original Research

Open Access Special Issue

The impact of Peyronie's disease on Portuguese men's mental health and sexual functioning

  • Henrique Pereira1,2

1Department of Psychology and Education, Faculty of Social and Human Sciences, University of Beira Interior, 6200-209 Covilhã, Portugal

2The Research Center in Sports Sciences, Health Sciences and Human Development (CIDESD), 5000-471 Vila Real, Portugal

DOI: 10.31083/jomh.2021.034

Submitted: 29 January 2021 Accepted: 04 March 2021

Online publish date: 26 April 2021

*Corresponding Author(s): Henrique Pereira E-mail: hpereira@ubi.pt

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Abstract

Purpose: The purpose of this study was to assess the impact of Peyronie's disease (PD) on Portuguese men's mental health and sexual functioning.

Materials and Methods: Study participants included 103 men diagnosed with PD who had attended urology appointments at two hospitals in Portugal. The participants' average age was 34.38 years old (SD = 13.77). The study utilized a variety of measurement instruments, encompassing a sociodemographic questionnaire, the Portuguese version of the Brief Symptoms Inventory-18, the Portuguese version of the Massachusetts General Hospital-Sexual Functioning Questionnaire, and a Questionnaire measuring PD concerns.

Results: Overall results showed that the men surveyed presented higher levels of mental health symptoms (somatization, depression, and anxiety) and lower levels of sexual functioning than the community sample (the general Portuguese population without clinical disorders). Correlation coefficients showed a strong and positive correlation between mental health symptoms and a loss of sexual confidence and stress, while finding a strong and negative correlation between sexual functioning and stress. Most PD concerns exhibited strong and positive mutual correlations. The study also found strong and positive correlations between penile curvature and a perceived reduction in penis attractiveness and discrimination fears. Multiple regression analyses showed that PD concerns and penile curvature explained 34.3% of the overall mental health variance and 21% of the overall sexual functioning variance.

Conclusions: These results are consistent with those of previous studies that have shown that experiencing PD can increase mental health symptoms and diminish sexual functioning.

Keywords

Peyronie's disease; Mental health; Sexual functioning; Portuguese men

Cite and Share

Henrique Pereira. The impact of Peyronie's disease on Portuguese men's mental health and sexual functioning. Journal of Men's Health. 2021.doi:10.31083/jomh.2021.034.

References

[1] Schwarzer U, Sommer F, Klotz T, Braun M, Reifenrath B, Engelmann U. The prevalence of Peyronie’s disease: results of a large survey. BJU International. 2001; 88: 727–730.

[2] Mulhall JP, Creech SD, Boorjian SA, Ghaly S, Kim ED, Moty A, et al. Subjective and objective analysis of the prevalence of Peyronie’s disease in a population of men presenting for prostate cancer screening. The Journal of Urology. 2004; 171: 2350–2353.

[3] DiBenedetti DB, Nguyen D, Zografos L, Ziemiecki R, Zhou X. A population-based study of Peyronie’s disease: prevalence and treatment patterns in the United States. Advances in Urology. 2011; 2011: 282503.

[4] Paulis G, Romano G, Paulis A. Prevalence, psychological impact, and risk factors of erectile dysfunction in patients with Peyronie’s disease: a retrospective analysis of 309 cases. Research and Reports in Urology. 2016; 8: 95–103.

[5] Diegelmann RF. Cellular and biochemical aspects of normal and abnormal wound healing: an overview. The Journal of Urology. 1997; 157: 298–302.

[6] Somers KD, Dawson DM. Fibrin deposition in Peyronie’s disease plaque. The Journal of Urology. 1997; 157: 311–315.

[7] Dolmans GH, Werker PM, de Jong IJ, Nijman RJ, Wijmenga C, Ophoff RA. WNT2 locus is involved in genetic susceptibility of Peyronie’s disease. The Journal of Sexual Medicine. 2012; 9: 1430–1434.

[8] Van de Water L. Mechanisms by which fibrin and fibronectin appear in healing wounds: implications for Peyronie’s disease. The Journal of Urology. 1997; 157: 306–310.

[9] Gonzalez-Cadavid NF. Mechanisms of penile fibrosis. The Journal of Sexual Medicine. 2009; 6: 353–362.

[10] Paulis G, Brancato T. Inflammatory mechanisms and oxidative stress in Peyronie’s disease. Therapeutic “rationale” and related emerging treatment strategies. Inflamm Allergy Drug Targets. 2012; 11: 48–57.

[11] Mulhall JP, Schiff J, Guhring P. An analysis of the natural history of Peyronie’s disease. The Journal of Urology. 2006; 175: 2115–2118; discussion 2118.

[12] Sikka SC, Hellstrom WJG. Role of oxidative stress and antioxidants in Peyronie’s disease. International Journal of Impotence Research. 2002; 14: 353–360.

[13] Kadioglu A, Sanli O, Akman T, Canguven O, Aydin M, Akbulut F, et al. Factors affecting the degree of penile deformity in Peyronie disease: an analysis of 1001 patients. Journal of Andrology. 2011; 32: 502–508.

[14] Pryor JP, Ralph DJ. Clinical presentations of Peyronie’s disease. International Journal of Impotence Research. 2002; 14: 414–417.

[15] Weidner W, Schroeder-Printzen I, Weiske WH, Vosshenrich R. Sexual dysfunction in Peyronie’s disease: an analysis of 222 patients without previous local plaque therapy. The Journal of Urology. 1997; 157: 325–328.

[16] Levine LA, Latchamsetty KC. Treatment of erectile dysfunction in patients with Peyronie’s disease using sildenafil citrate. International Journal of Impotence Research. 2002; 14: 478–482.

[17] Levine L. Peyronie’s disease and erectile dysfunction: current under-standing and future direction. Indian Journal of Urology. 2006; 22: 246.

[18] Deveci S, Palese M, Parker M, Guhring P, Mulhall JP. Erectile function profiles in men with Peyronie’s disease. The Journal of Urology. 2006; 175: 1807–1811.

[19] Rosen R, Catania J, Lue T, Althof S, Henne J, Hellstrom W, et al. Impact of Peyronie’s disease on sexual and psychosocial functioning: qualitative findings in patients and controls. The Journal of Sexual Medicine. 2008; 5: 1977–1984.

[20] Smith JF, Walsh TJ, Conti SL, Turek P, Lue T. Risk factors for emotional and relationship problems in Peyronie’s disease. The Journal of Sexual Medicine. 2008; 5: 2179–2184.

[21] Gelbard MK, Dorey F, James K. The natural history of Peyronie’s disease. The Journal of Urology. 1990; 144: 1376–1379.

[22] Nelson CJ, Diblasio C, Kendirci M, Hellstrom W, Guhring P, Mulhall JP. The chronology of depression and distress in men with Peyronie’s disease. The Journal of Sexual Medicine. 2008; 5: 1985–1990.

[23] Hartzell R. Psychosexual symptoms and treatment of Peyronie’s disease within a collaborative care model. Sexual Medicine. 2014; 2: 168–177.

[24] Terrier JE, Nelson CJ. Psychological aspects of Peyronie’s disease. Translational Andrology and Urology. 2016; 5: 290–295.

[25] Nazaré B, Pereira M, Canavarro MC. Avaliação breve da psicossin-tomatologia: Análise fatorial confirmatória da versão portuguesa do Brief Symptom Inventory 18 (BSI 18). Analysis of the Physiological. 2017; 35: 213–230.

[26] Pereira H. Psychometric validation of the Portuguese version of the Massachusetts General Hospital - Sexual Functioning Questionnaire. Revista Internacional de Andrologia. 2018; 16:102–106. (in Por-tuguese)

[27] Nelson CJ, Mulhall JP. Psychological impact of Peyronie’s disease: a review. The Journal of Sexual Medicine. 2013; 10: 653–660.

[28] Rosen R, Catania J, Lue T, Althof S, Henne J, Hellstrom W, et al. Impact of Peyronie’s disease on sexual and psychosocial functioning: qualitative findings in patients and controls. The Journal of Sexual Medicine. 2008; 5: 1977–1984.

[29] Di Maida F, Cito G, Lambertini L, Valastro F, Morelli G, Mari A, et al. The natural history of Peyronie’s disease. World Journal of Men’s Health. 2020; 38: e34.

[30] Salter CA, Nascimento B, Terrier JE, Taniguchi H, Bernie H, Miranda E, et al. Defining the impact of Peyronie’s disease on the psychosocial status of gay men, et al. Defining the impact of Peyronie’s disease on the psychosocial status of gay men. Andrology. 2021; 9: 233-–237.

[31] Punjani N, Nascimento B, Salter C, Miranda E, Terrier J, Taniguchi H, et al. Predictors of Depression in Men With Peyronie’s Disease Seeking Evaluation. The Journal of Sexual Medicine. 2021. (in press)

[32] Nehra A, Alterowitz R, Culkin DJ, Faraday MM, Hakim LS, Hei-delbaugh JJ, et al. Peyronie’s disease: AUA guideline. The Journal of Urology. 2015; 194: 745–753.

[33] Burri A, Porst, H. The relationship between penile deformity, age, psychological bother, and erectile dysfunction in a sample of men with Peyronie’s Disease (PD). International Journal of Impotence Research. 2018; 30: 171–178.

[34] Pereira H, Monteiro S, Esgalhado G, Afonso RM, Loureiro M. Psychosocial determinants of sexual functioning and subjective sexual well‐being in Portuguese Adult Men. Revista internacional de An-drología. 2017; 15: 90–98.


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