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Original Research

Open Access

ASSOCIATIONS BETWEEN PITUITARY-GONADAL AXIS PARAMETERS AND SEMEN QUALITY IN YOUNG, HEALTHY MEN (AndroLS)

  • Józ´ków Paweł1
  • Me˛dras´ Marek1,2
  • Szmigiero Leszek3
  • Słowin´ska-Lisowska Małgorzata1
  • Lwow Felicja4

1Department of Sports Medicine & Dietetics, University School of Physical Education, Wrocław, Poland

2Department of Endocrinology, Diabetology & Isotope Therapy, Wroclaw Medical University, Wrocław, Poland

3Department of Nucleic Acid Biochemistry, Medical University of Lodz, Łódz´, Poland

4Department of Health Promotion, Faculty of Physiotherapy, University School of Physical Education, Wrocław, Poland

DOI: 10.22374/jomh.v15i3.143 Vol.15,Issue 3,July 2019 pp.11-24

Published: 02 July 2019

*Corresponding Author(s): Józ´ków Paweł E-mail: jozkow@gmail.com

Abstract

Background and Objective

Hormonal measurements play an important role in the evaluation of male fertility potential. In men without hypogonadism, the impact of androgen status on semen is rarely analyzed.

Material and Methods

We evaluated associations between parameters of the pituitary-gonadal axis: luteinizing hormone (LH), follicle-stimulating hormone (FSH), total testosterone (T), free testosterone (FT), calculated testosterone (TC), bioavailable testosterone (TB), sex hormone-binding globulin (SHBG), free andro-gen index, and semen quality parameters in healthy young men.

Results

In our study group, sperm concentration and sperm count were associated with FSH and FT. The percentage of immotile sperm was associated with LH and T. The percentage of vital sperm was negatively related to LH. We identified negative, independent associations between T and semen volume (p<0.026) and TC and semen volume (p<0.025). We observed negative, independent associ-ation between FSH, FT, and total sperm count (both P<0.002) and between FT and the percentage of normal forms (P<0.012). There were positive associations between LH and T and the percentage of immotile sperm (P<0.007 and P<0.034, respectively). There were no relationships between sperm morphology parameters and the parameters of the pituitary-gonadal axis.

Conclusion

In healthy eugonadal men, variations in FSH, LH, T, and FT (within normal limits) are reflected in semen characteristics but not in sperm morphology features.

Keywords

luteinizing hormone, follicle stimulating hormone, testosterone, semen quality, hormones 

Cite and Share

Józ´ków Paweł,Me˛dras´ Marek,Szmigiero Leszek,Słowin´ska-Lisowska Małgorzata,Lwow Felicja. ASSOCIATIONS BETWEEN PITUITARY-GONADAL AXIS PARAMETERS AND SEMEN QUALITY IN YOUNG, HEALTHY MEN (AndroLS). Journal of Men's Health. 2019. 15(3);11-24.

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