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Original Research

Open Access

ASSOCIATION OF THE SERUM IGG LEVEL AGAINST PERIODONTAL BACTERIA WITH PERIODONTAL STATUS AND SERUM LIPID LEVELS

  • Reiko Furugen1
  • Hideaki Hayashida1
  • Koji Kawasaki2
  • Masayasu Kitamura1
  • Takahiro Iwasaki3
  • Toshiyuki Saito1
  • Takahiro Maeda4

1Department of Oral Health, Nagasaki University Graduate School of Biomedical Sciences

2Community Medical Network Center, Nagasaki University Hospital

3Department of Community Oral Health, School of Dentistry, Asahi University

4Department of Island and Community Medicine, Nagasaki University Graduate School of Biomedical Sciences

DOI: 10.22374/1875-6859.14.4.3 Vol.14,Issue 4,September 2018 pp.11-17

Published: 24 September 2018

*Corresponding Author(s): Hideaki Hayashida E-mail: hide@nagasaki-u.ac.jp

PDF (1.87 MB)

Abstract

Background and Objective

Several studies have reported that serum antibodies against periodontal pathogens are related not only to periodontal status but also to systemic conditions, such as glycemic control and serum lipids. Therefore, this study examined the associations of serum IgG antibodies against periodontal pathogens with periodontal status and serum lipid levels in community dwellers.

Materials and Methods

A community-based cross-sectional study of 409 subjects (140 men, 269 women) aged ≥ 40 years who had at least 5 teeth was conducted in Goto, Japan in 2009 and 2010.

Results

The serum IgG levels against Porphyromonas gingivalis were significantly associated with periodontal parameters and serum high-density lipoprotein cholesterol (HDL-C) in men. According to a multiple linear regression analysis adjusted for covariates, the serum IgG levels against P. gingivalis were inversely related to serum HDL-C (B = −0.1; P = 0.004).

Conclusion

This study suggests that an elevated immune response to the periodontal pathogen is independently cor-related with lower serum HDL-C level in community-dwelling men.

Keywords

Periodontitis; Periodontal bacteria; Serum IgG antibody, HDL-cholesterol

Cite and Share

Reiko Furugen,Hideaki Hayashida,Koji Kawasaki,Masayasu Kitamura,Takahiro Iwasaki,Toshiyuki Saito,Takahiro Maeda. ASSOCIATION OF THE SERUM IGG LEVEL AGAINST PERIODONTAL BACTERIA WITH PERIODONTAL STATUS AND SERUM LIPID LEVELS. Journal of Men's Health. 2018. 14(4);11-17.

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