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Original Research

Open Access


  • Jian-Kang Chao1,2
  • Mi-Chia Ma3
  • I-Hsin Candy Chao4

1Department of Psychiatry, Yuli branch, Taipei Veterans General Hospital, Hualien, Taiwan

2Department of social work, National Pingtung University of Science and Technology, Pingtung, Taiwan

3Department of Statistics, National Cheng Kung University, Tainan, Taiwan

4Faculty of Business, University of Technology Sydney, Sydney, Australia

DOI: 10.22374/1875-6859.14.4.2 Vol.14,Issue 4,September 2018 pp.25-37

Published: 24 September 2018

*Corresponding Author(s): Jian-Kang Chao E-mail:

PDF (3.87 MB)


Background and Objective

The overall prevalence of metabolic syndrome (MetS) and obesity in male Taiwanese is very high, but the impacts on MetS, sexuality and sex hormones, inflammation markers in male erectile dysfunction (ED) are not entirely clear in relevance. This study’s aim is to investigate males with MetS and its components, sex hormones, inflammatory risk factors, sexuality and ED correlation.

Material and Methods

This was a cross-sectional study of 89 male participants, and data collected included demographic data, biochemistry, sex hormones, inflammatory risk factors and International Index of Erectile Function (IIEF-15) questionnaire. Descriptive analysis, difference analysis, and logistic regression model were used to identify relevant variables that may affect ED.


Among our 89 subjects, 46 had MetS (51.7%) and 31 subjects with MetS had ED (67.4%). The presence of MetS had a significant correlation with lower IIEF-ED scores, lower intercourse satisfaction scores, lower total testosterone (TT) serum level (p<0.01) and also presence of MetS had a significant correlation with higher D-dimer, fibrinogen and  C-reactive protein (CRP) serum level. The results also showed that the greater the number of MetS components had the higher the prevalence of ED and the higher the abnormal CRP, fibrinogen and D-dimer (p<0.05). After adjusting for age, we used sexual desire dysfunction, Met S and TT abnormal to run the logistic regression model for predictors of ED, and the analysis showed that there was a significant difference for sexual desire dysfunction (OR = 8.845, 95% CI=2.203 – 35.516, P = 0.002), Met S (OR = 4.100, 95% CI = 1.343 – 12.520, P = 0.013) and TT abnormal (OR = 3.287, 95% CI = 1.022 – 10.570, P = 0.046).


To prevent the development of ED, we should encourage a change in lifestyle to prevent the development of MetS, and early identification and treatment of MetS risk factors might be helpful to prevent ED and secondary cardiovascular disease, including diet and lifestyle interventions.


erectile dysfunction; metabolic syndrome; International Index of Erectile Function; testos-terone; inflammatory risk factors

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