FEBRILE URINARY TRACT INFECTION AFTER RADICAL CYSTECTOMY WITH URINARY DIVERSION: DIFFERENT CHARACTERISTICS IN PATIENTS WITH ILEAL CONDUIT AND ORTHOTOPIC NEOBLADDER
1Department of Urology, Pusan National University Yangsan Hospital, Yangsan, Korea
2Department of Urology, Pusan National University Hospital, Busan, Korea
DOI: 10.15586/jomh.v16i3.246 Vol.16,Issue 3,July 2020 pp.38-46
Published: 16 July 2020
Background and Objective
To compare the incidence of febrile urinary tract infection (UTI) and bacterial identification between patients with orthotopic neobladder (ONB) and ileal conduit (IC).
Materials and Methods
Data of 164 patients who underwent radical cystectomy with ONB and IC for bladder cancer between January 2009 and January 2018 at our institution were analyzed. Febrile UTI observed was listed and subsequently compared. Incidence of febrile UTI, clinicopathological characteristics, and microorganisms identified were reported at 3 months interval; and preoperative predictors of febrile UTI were evaluated with Cox regression analysis. Patients were divided into ONB and IC.
The study cohort included 52 patients with ONB and 112 patients with IC. Febrile UTI was diagnosed in 49 (29.9%) patients. Compared to IC group, ONB group had significantly higher incidence of young age (p=0.00), lower cancer stage (p=0.013), longer hospital stay (p=0.049), longer operation time (p=0.00), and higher incidence of febrile UTI within the first 3 months after surgery (p=0.006). On univariable and multivariable analysis, factors associated with significantly increased febrile UTI risk were diabetes (odds ratio [OR]: 4.52; p=0.002) and ONB diversion (OR: 1.27; p=0.031). Forty-four (89.8%) patients were culture positive. However, significant difference in microorganisms was not detected between patients who under-went ONB or IC diversion.
Diabetes and ONB diversion were associated with higher risk symptomatic UTI following radical cystectomy.
urinary tract infections; urinary bladder neoplasms; urinary diversion
Seungsoo Lee,Seung Ryong Baek,Won Hoon Song,Tae Nam Kim,Sung-Woo Park,Jong Kil Nam. FEBRILE URINARY TRACT INFECTION AFTER RADICAL CYSTECTOMY WITH URINARY DIVERSION: DIFFERENT CHARACTERISTICS IN PATIENTS WITH ILEAL CONDUIT AND ORTHOTOPIC NEOBLADDER. Journal of Men's Health. 2020. 16(3);38-46.
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