Physical Activity and Cardiorespiratory Fitness Attenuate the Impact of Sarcopenic-Obesity on Cardiovascular Disease Risk in Korean Men

Main Article Content

Shinuk Kim

Keywords

sarcopenia, obesity, cardiovascular disease, physical activity, physical fitness.

Abstract

Background and objective
The role of physical activity (PA) and fitness with respect to the relationship between sarcopenic obe-sity and cardiovascular disease (CVD) risk in Korean men is poorly understood. This study investi-gated whether or not PA and cardiorespiratory fitness (CRF) attenuate the synergistic impact of sarcopenic obesity on CVD risk in a sample of Korean men aged 40 years and older.


Material and methods
This study analyzed data (n=3089 men aged 40 years and older) obtained from the KNHANES IV and V. Participants were classified into four groups: the absence of both sarcopenia and obesity called optimal body composition, the presence of sarcopenia only, the presence of obesity only, or the coex-istence of sarcopenia and obesity defined as sarcopenic obesity. The 10-year Framingham risk score model was used to estimate CVD risk, which was classified into low (<10%), intermediate (10–20%), and high (>20%) categories. PA was assessed with the Korean version of the International Physical Activity Questionnaire. CRF was estimated using nonexercise-based health indicators such as gender, age, resting heart rate, and PA score.


Results
Logistic regression analyses showed that the odds ratios (ORs) for ≥10% 10-year CVD risk were sig-nificantly higher in the order of obesity (OR=1.717, p<0.001), sarcopenia (OR=2.290, p<0.001), and sarcopenic obesity (OR=3.568, p<0.001) compared to optimal (OR=1). The ORs of ≥10% 10-year CVD risk remained statistically significant even after adjustment for age, education, and income but were no longer significant after additional adjustment for PA and CRF.


Conclusion
The current findings suggest that high PA and CRF attenuate the synergistic impact of sarcopenia and obesity on CVD risk in Korean men, implying a clinical importance of interventions targeting low PA and poor CRF for men with sarcopenic obesity.

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