Journal of Mens Health <p>The Journal of Men’s Health (JOMH) is a peer-reviewed publication covering all aspects of men’s health across the lifespan. As the official journal the International Society of Men’s Health (ISMH) the Journal publishes cutting-edge advances in a wide range of diseases and conditions, including diagnostic procedures, therapeutic management strategies, and innovative clinical research in gender-based biology to ensure optimal patient care. The Journal addresses disparities in health and life expectancy between men and women; increased risk factors such as smoking, alcohol abuse, and obesity; higher prevalence of diseases such as heart disease and cancer; and health care in underserved and minority populations.<br><br><br></p> <p><br><br></p> en-US Journal of Mens Health 1875-6859 Effects of Acupuncture Therapy on the EMG Activity of the Rectus Femoris and Tibialis Anterior during Maximal Voluntary Isometric Contraction in College Students <p>Acupuncture has been increasingly used in the treatment of muscle damage associated with sports activities. However, studies on the immediate effects of one-time acupuncture on the muscles of athletes are clearly lacking. Thus, this study aimed to examine the effects of acupuncture therapy on the maximal voluntary isometric contraction (MVIC) electromyography (EMG) of the rectus femoris and tibialis anterior muscles. This study was conducted among 20 healthy male college students who had no musculoskeletal disease. The participants were subjected to 3 different experimental conditions and subsequently grouped based on these conditions: real acupuncture, sham acupuncture, and control. A 7-day washout period was implemented to avoid any transient effects on the physiological and psychological conditions of the participants. Subsequently, an electromyogram patch was attached on the most developed area in the middle of the origin and insertion of the rectus femoris and tibialis anterior muscles. The percent MVIC, which was used to standardize the signal from the electromyogram, was determined, and the maximal value from the MVIC of the rectus femoris and tibialis anterior muscles was measured. The MVIC EMG activities of both femoris (F = 6.633, p = 0.003) and tibialis anterior (F = 5.216, p = 0.008) muscles were significantly different among all groups. Accordingly, the results of a posthoc test showed that the real acupuncture group had higher MVIC EMG activities in the femoris (p = 0.002) and tibialis anterior (p = 0.006) muscles compared with the control group. These results suggest that treatment with real acupuncture resulted in significantly higher MVIC EMG activities of the rectus femoris and tibialis anterior muscles than the other treatments. Hence, acupuncture may be helpful in the improvement of muscle strength among athletes in the physical fitness field.</p> Se In Jang Wi-Young So Copyright (c) 2017 Journal of Mens Health 2017-12-20 2017-12-20 14 1 e1 e5 Effects of a Single Bout of Aerobic Exercise on Skeletal Muscle Protein Turnover in Mice <p><strong>Background and Objective</strong>: The effect of a single bout of aerobic exercise on regulation of protein balance remains unknown. In the present study, we investigated the effect of a single bout of treadmill-based exercise on the levels of various protein synthesis-related eukaryotic proteins (initiation factor 2a, eukaryotic initiation factor 4E, eukaryotic initiation factor 4E-binding protein 1, and eukaryotic elongation factor 2), breakdown-related proteins (microtubule-associated protein 1 light chain 3 alpha (LC3), autophagy-related 7, and muscle RING-finger protein 1 (MuRF1)), and polyubiquitination in 3-month-old male ICR mice.</p> <p><strong>Material and Methods:</strong> Twenty-four male mice were randomized into four time-point groups, and each group of mice run on a rodent treadmill for 10 min at 10 m/min at a slope of 5° between 7:00 p.m. and 8:00 p.m. for 2 days during the adaptation period. On the third day, exercise was performed for 50 min at a speed of 12.3 m/min, except for the control mice that did not perform any exercise. Gastrocnemius muscles were collected immediately after the mice were sacrificed by cervical dislocation at 0, 3, 6, or 12 h post-exercise.</p> <p><strong>Results:</strong> Levels of synthesis-related proteins were significantly reduced at 3 and 6 h into the recovery period, whereas levels of breakdown-related proteins, including that of the autophagy marker LC3, increased immediately after exercise but not during the recovery period. MuRF1 level was determined in the gastrocnemius muscle to identify the factors involved in this increase. We show that increased MuRF1 levels were associated with an increase in polyubiquitination during the recovery period.</p> <p><strong>Conclusion:</strong> Our results suggest a potential role of optimal time points in muscle protein metabolism during recovery from a single bout of treadmill exercise.</p> Yong-An Kim Wi-Young So Copyright (c) 2017 Journal of Mens Health 2017-12-18 2017-12-18 14 1 e6 e15 Is There a Minimally Invasive Day Case Operation to Treat LUTS Secondary to BPH and Avoid Sexual Dysfunction? UroLift A Case Report <p><strong><em>Abstract</em></strong></p> <p>A 75 year old Caucasian male with a prolonged history of lower urinary tract symptoms and sexual dysfunction was referred to the urology department. Assessment revealed a diagnosis of benign prostatic hypertrophy (BPH) and the patient was reassessed by flexible cystoscopy revealing a large occlusive 80cc prostate. Baseline symptoms of BPH were measured using the International Prostate Symptom Score (IPSS), urinary function was quantified by measuring post void residual (PVR) volume and QMAX flow rates were also recorded. The patient underwent the Urolift procedure and urological parameters were reassessed at 4 months post-operatively. There was an improvement in the patients IPSS by 14 points (IPSS Before =22, at 4 months =8), with a reduction in quality of life by 3 points (QoL before = 5, at 4 months =2).PVR volume decreased by almost a third (29.4 %) (Before = 390ml, at 4 months = 275 ml) and QMAX improved by 8 ml/s (Before =14ml/s, at 4 months= 22ml/s). The patient reported a slight improvement in sexual function (IIEF-5 Before = 14, at 4 months = 15) and was very satisfied with the result. The improvement in IPSS, PVR volume and QMAX show Urolift is an appropriate treatment for symptomatic BPH.</p> Antonio Devanti Bardoli Will Taylor Wasim Mahmalji Jon Cobley Copyright (c) 2018 Journal of Mens Health 2018-01-02 2018-01-02 14 1 e16 e18 The rarest form of Paratesticular Leiomyosarcoma – a case report <p>Paratesticular tumours make up less than 5% of intra-scrotal tumours and of these, approximately 30% are malignant tumours with sarcomas accounting for the majority.</p> <p>Leiomyosarcoma is a malignant tumour arising from soft tissues containing smooth muscle. They are reported as comprising between 5-30% of paratesticular sarcomas<sup>1,2</sup>. It is extremely rare that they arise from tissue other than the spermatic cord or epididymis.</p> <p>We describe such a case of paratesticular leiomyosarcoma in a fifty-four year old man who presented with a six month history of a painful testis and who subsequently underwent radical inguinal orchidectomy and high ligation.</p> Jonathan Joseph Cobley Wasim Mahmalji Copyright (c) 2018 Journal of Mens Health 2018-01-15 2018-01-15 14 1 e19 e21